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  2. Polyclonal

600-401-EF0

SCUBE2 Antibody

Cannot supply to this region.

SKU:
600-401-EF0
Additional Names:
SCUBE2|SCUBE2 Antibody, CEGB1, CEGF1, CEGP1, Signal peptide, CUB and EGF-like domain-containing protein 2, Protein CEGP1
Application:
ELISA, IHC, WB, IF
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:
Anti-SCUBE2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the internal region of human SCUBE2.
Formulation:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:
Q9NQ36
Synonyms:
CEGB1;CEGF1;CEGP1;Protein CEGP1;scube/You;signal peptide, CUB and EGF-like domain-containing protein 2
Extra Details:
SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.
Shipping Conditions:
Dry Ice