600-401-ED7
SAMHD1 Antibody
Cannot supply to this region.
- SKU:
- 600-401-ED7
- Additional Names:
- SAM domain and HD domain 1, DCIP, CHBL2, HDDC1, MOP-5, SBBI88|SAMHD1
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-SAMHD1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human SAMHD1.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9Y3Z3
- Synonyms:
- CHBL2;DCIP;dendritic cell-derived IFNG-induced protein;deoxynucleoside triphosphate triphosphohydrolase SAMHD1;dNTPase;HDDC1;hSAMHD1;monocyte protein 5;MOP-5;SAM domain and HD domain 1;SAM domain and HD domain-containing protein 1;SBBI88
- Extra Details:
- The SAM domain and HD domain 1 (SAMHD1) protein is upregulated in response to viral infection and is thought to play a role in innate immunity (1). SAMHD1 blocks the infection of HIV-1 and SIVdeltaVpx before reverse transcription in macrophages and dendritic cells (2), and this restriction is regulated by phosphorylation of SAMHD1 (3). Mutations in this gene have been associated with Aicardi-Goutieres syndrome (1).
- Shipping Conditions:
- Dry Ice