600-401-ED6
SAE2 Antibody
Cannot supply to this region.
- SKU:
- 600-401-ED6
- Additional Names:
- SAE2 Antibody, ARX, SAE2, HRIHFB2115, UBLE1B, SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX|UBA2
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-SAE2 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the C-terminus of human SAE2.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9UBT2
- Synonyms:
- anthracycline-associated resistance ARX;ARX;HRIHFB2115;SAE2;SUMO-1 activating enzyme subunit 2;SUMO-activating enzyme subunit 2;SUMO1 activating enzyme subunit 2;UBA2, ubiquitin-activating enzyme E1 homolog;ubiquitin-like 1-activating enzyme E1B;Ubiquitin-like modifier-activating enzyme 2
- Extra Details:
- Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.
- Shipping Conditions:
- Dry Ice