600-401-E23
Raf-1 phospho S301 Antibody
Cannot supply to this region.
- SKU:
- 600-401-E23
- Additional Names:
- RAF proto-oncogene serine/threonine-protein kinase, Proto-oncogene c-RAF, cRaf|Raf1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Rat
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- Immunogen:
- Anti-Raf-1 pS301 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser301 conjugated to KLH.
- Formulation:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Uniprot:
- P11345
- Synonyms:
- C-RAF;cRaf;murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV);proto-oncogene c-RAF;RAF proto-oncogene serine/threonine-protein kinase;Raf-1;v-raf-1 murine leukemia viral oncogene homolog 1;v-raf-leukemia viral oncogene 1
- Extra Details:
- Raf-1 pS301 antibody detects phosphorylated Raf-1. The Ras pathway is a critical signal transduction cascade involved in regulating cellular proliferation, differentiation, survival, and oncogenic transformation. Members of the Raf serine/threonine kinase family are key intermediates in this cascade, functioning to relay signals from activated Ras to the downstream protein kinases MEK and ERK. Previous studies have shown that phosphorylation is required for Raf-1 activation. Recent work has demonstrated that phosphorylation also regulates the downregulation of Raf with two sites participating: Ser301 and Ser642. Anti-Raf-1 pS301 Antibody is ideal for investigators involved in Cancer, Neuroscience, Signal Transduction research.
- Shipping Conditions:
- Dry Ice