600-401-E12
Polo-Like Kinase phospho S482/phospho S486/phospho S490 Antibody
Cannot supply to this region.
- SKU:
- 600-401-E12
- Additional Names:
- PLK1|Serine/threonine-protein kinase PLK1, Plx1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Amphibian
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- Immunogen:
- Anti-Polo-like Kinase pS482/pS486/pS490 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser392482/486/490.
- Formulation:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Uniprot:
- P53350.1
- Synonyms:
- plk;PLK-1;plk1;plx1;polo-like kinase 1;Serine/threonine-protein kinase 13;serine/threonine-protein kinase PLK1;XELAEV_18047692mg
- Extra Details:
- Polo-Like Kinase pS482/pS486/pS490 detects Polo-Like Kinase proteins. Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK. Anti-Polo-Like Kinase pS482/pS486/pS490 Antibody is ideal for investigators involved in Cell Cycle and Apoptosis research.
- Shipping Conditions:
- Dry Ice