600-401-DR9
PPAPDC3 Antibody
Cannot supply to this region.
- SKU:
- 600-401-DR9
- Additional Names:
- PLPP7|PPAPDC3 Antibody, NET39, C9orf67, Probable lipid phosphate phosphatase PPAPDC3, Phosphatidic acid phosphatase type 2 domain-containing protein 3
- Application:
- ELISA, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-PPAPDC3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide from near the amino of terminus human PPAPDC3.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q8NBV4
- Synonyms:
- C9orf67;epididymis secretory sperm binding protein;inactive phospholipid phosphatase 7;NET39;nuclear envelope transmembrane protein NET39;phosphatidic acid phosphatase type 2 domain containing 3;phosphatidic acid phosphatase type 2 domain-containing protein 3;PPAPDC3;probable lipid phosphate phosphatase PPAPDC3
- Extra Details:
- PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.
- Shipping Conditions:
- Dry Ice