600-401-DK9
PEAR1 Antibody
Cannot supply to this region.
- SKU:
- 600-401-DK9
- Additional Names:
- PEAR1|PEAR1 Antibody, JEDI, MEGF12, Platelet endothelial aggregation receptor 1, Multiple epidermal growth factor-like domains protein 12, hPEAR1
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-PEAR1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of human PEAR1.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q5VY43
- Synonyms:
- JEDI;MEGF12;multiple EGF-like domains protein 12;multiple EGF-like-domains 12;multiple epidermal growth factor-like domains protein 12;platelet endothelial aggregation receptor 1
- Extra Details:
- Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.
- Shipping Conditions:
- Dry Ice