600-401-CV1
MORF4 Antibody
Cannot supply to this region.
- SKU:
- 600-401-CV1
- Additional Names:
- MORF4|MORF4 Antibody, CSR, SEN, CSRB, SEN1, Mortality Factor 4 (Pseudogene), Senescence (Cellular)-Related, Mortality Factor 4 Like 1 Pseudogene, Senescence-Related Cellular 1, Mortality Factor 4
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-MORF4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid synthetic peptide from near the N-terminus of human MORF4.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Synonyms:
- CSR;CSRB;mortality factor 4 like 1 pseudogene;SEN;SEN1;senescence (cellular)-related 1;senescence-related, cellular, 1
- Extra Details:
- Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
- Shipping Conditions:
- Dry Ice