600-401-CS8
ME1 Antibody
Cannot supply to this region.
- SKU:
- 600-401-CS8
- Additional Names:
- ME1|ME1 Antibody, MES, HUMNDME, NADP-dependent malic enzyme, Malic enzyme 1, NADP-ME
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-ME1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the N-terminus of human ME1.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P48163
- Synonyms:
- HUMNDME;malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+));Malic enzyme 1;malic enzyme 1, NADP(+)-dependent, cytosolic;malic enzyme 1, soluble;Malic enzyme, cytoplasmic;MES;NADP-dependent malic enzyme;NADP-ME;pyruvic-malic carboxylase
- Extra Details:
- ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1). ME1 is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family (2). It is expressed ubiquitously with highest expression in liver and white adipose tissue. ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3). The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4). ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5).
- Shipping Conditions:
- Dry Ice