600-401-CQ4
MAP1LC3 Antibody
Cannot supply to this region.
- SKU:
- 600-401-CQ4
- Additional Names:
- MAP1LC3 Antibody, LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3Autophagy-related protein LC3 A|MAP1LC3A
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-MAP1LC3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 12 amino acid peptide near the internal region of human MAP1LC3A.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9H492
- Synonyms:
- ATG8E;Autophagy-related protein LC3 A;autophagy-related ubiquitin-like modifier LC3 A;LC3;LC3A;MAP1 light chain 3-like protein 1;MAP1A/1B light chain 3 A;MAP1A/MAP1B LC3 A;MAP1A/MAP1B light chain 3 A;MAP1ALC3;MAP1BLC3;Microtubule-associated protein 1 light chain 3 alpha;microtubule-associated proteins 1A/1B light chain 3;microtubule-associated proteins 1A/1B light chain 3A
- Extra Details:
- Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3 is a subfamily of three related proteins belonging to the MAP1 LC3 family and it includes MAP1LC3A, MAP1LC3B, and MAP1LC3C (2). MAP1LC3 is the mammalian homolog of yeast ATG8 and is essential for autophagy and associated with the autophagosome membranes after processing (3). The three isoforms exhibit distinct expression patterns and both MAP1LC3A and MAP1LC3B but not MAP1LC3B, are post-translationally modified, suggesting the three isoforms may have different physiological functions (4).
- Shipping Conditions:
- Dry Ice