600-401-CL6
LMX1A Antibody
Cannot supply to this region.
- SKU:
- 600-401-CL6
- Additional Names:
- LMX1A|LMX1A Antibody, LMX1, LMX1.1, LIM homeobox transcription factor 1-alpha
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti- LMX1A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the C-terminus of human LMX1A.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q8TE12
- Synonyms:
- DFNA7;LIM homeobox transcription factor 1-alpha;LIM/homeobox protein 1.1;LIM/homeobox protein LMX1A;LMX1;LMX1.1
- Extra Details:
- The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.
- Shipping Conditions:
- Dry Ice