LGP2 Antibody

Cannot supply to this region.

SKU:: 600-401-CK2
Additional Names:: DHX58|LGP2 Antibody, LGP2, RLR-3, D11LGP2, D11lgp2e, D11LGP2E, LGP2, Probable ATP-dependent RNA helicase DHX58, Probable ATP-dependent helicase LGP2
Application:: ELISA, WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:: Anti-LGP2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide from near the N-terminus of human LGP2.
Formulation:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:: Q96C10
Synonyms:: D11LGP2;D11lgp2e;DEXH (Asp-Glu-X-His) box polypeptide 58;LGP2;ortholog of mouse D11lgp2;probable ATP-dependent helicase LGP2;probable ATP-dependent RNA helicase DHX58;protein D11Lgp2 homolog;RIG-I-like receptor 3;RIG-I-like receptor LGP2;RLR;RLR-3;RNA helicase LGP2
Extra Details:: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.

Shipping Conditions:: Dry Ice