600-401-CD7
KCNK12 Antibody
Cannot supply to this region.
- SKU:
- 600-401-CD7
- Additional Names:
- KCNK12|KCNK12 Antibody, THIK2, THIK-2, K2p12.1, Potassium channel subfamily K member 12, Tandem pore domain halothane-inhibited potassium channel 2
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-KCNK12 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the C-terminus of human KCNK12.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9HB15
- Synonyms:
- K2p12.1;potassium channel subfamily K member 12;potassium channel, subfamily K, member 12;potassium channel, two pore domain subfamily K, member 12;tandem pore domain halothane-inhibited potassium channel 2;tandem pore domain potassium channel THIK-2;THIK-2;THIK2
- Extra Details:
- KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.
- Shipping Conditions:
- Dry Ice