600-401-BZ0
IQSEC2 Antibody
Cannot supply to this region.
- SKU:
- 600-401-BZ0
- Additional Names:
- IQ motif and Sec7 domain 2, Brefeldin-resistant Arf-GEF 1 protein, BRAG1, MRX1|IQSEC2
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-IQSEC2 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human IQSEC2.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q5JU85
- Synonyms:
- BRAG1;brefeldin A resistant Arf-guanine nucleotide exchange factor 1;brefeldin A resistant Arf-guanine nucleotide exchange factor 1b;brefeldin A resistant Arf-guanine nucleotide exchange factor 1c;IQ motif and Sec7 domain 2;IQ motif and SEC7 domain-containing protein 2;IQ-ArfGEF;mental retardation, X-linked 18;MRX1;MRX18;MRX78;XLID1
- Extra Details:
- ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation. Similar to the related protein IQSEC1, IQSEC2 is a guanine nucleotide exchange protein for ARF1 and ARF6 that belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain (1,2). IQSEC2 is a major component of the postsynaptic density (PSD) and colocalizes with PSD-95. It has been suggested to modulate the functions of the ARF proteins (1). Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation (3).
- Shipping Conditions:
- Dry Ice