ILPIP Antibody

Cannot supply to this region.

SKU:: 600-401-BY1
Additional Names:: ILPIP Antibody, PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038, STE20-related kinase adapter protein beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, STRAD beta|STRADB
Application:: ELISA, IHC, WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:: Anti-ILPIP antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids at the C-terminus of human ILPIP.
Formulation:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:: Q9C0K7
Synonyms:: ALS2CR2;amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2;amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein;CALS-21;ILP-interacting protein;ILP-interacting protein ILPIPA;ILPIP;ILPIPA;PAPK;PRO1038;pseudokinase ALS2CR2;STE20-related kinase adapter protein beta;STE20-related kinase adaptor beta;STRAD beta
Extra Details:: ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1b converting enzyme of Fas-induced apoptosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.

Shipping Conditions:: Dry Ice