600-401-BX7
IL-37 Antibody
Cannot supply to this region.
- SKU:
- 600-401-BX7
- Additional Names:
- IL-37 Antibody , FIL1, FIL1Z, IL-1H, IL-37, IL1F7, IL1H4, IL-1F7, IL-1H4, IL1RP1, IL-1RP1, FIL1(ZETA), Interleukin-37, FIL1 zeta|IL37
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-IL-37 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the N-terminus of human IL-37.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9NZH6
- Synonyms:
- FIL1;FIL1 zeta;FIL1(ZETA);FIL1Z;IL-1 zeta;IL-1F7;IL-1F7b (IL-1H4, IL-1H, IL-1RP1);IL-1H;IL-1H4;IL-1RP1;IL-1X;IL-1X protein;IL-23;IL-37;IL1F7;IL1F7 (canonical product IL-1F7b);IL1H4;IL1RP1;interleukin 1 family member 7;interleukin 1, zeta;Interleukin-1 family member 7;interleukin-1 homolog 4;interleukin-1 superfamily z;Interleukin-1 zeta;interleukin-1-related protein;interleukin-23;interleukin-37
- Extra Details:
- Interleukin 37 (IL-37) is a member of the interleukin 1 cytokine family (reviewed in 1). It can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). IL-37 also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18 (1). IL-37 can also interact with Smad3 and expression of IL-37 in macrophages or epithelial cells resulted in near complete suppression of pro-inflammatory cytokines, suggesting that IL-37 may act as a natural suppressor of the innate inflammatory and immune responses (2,3).
- Shipping Conditions:
- Dry Ice