600-401-BX4
IL-36B Antibody
Cannot supply to this region.
- SKU:
- 600-401-BX4
- Additional Names:
- IL-36B Antibody, FIL1, FIL1H, IL1F8, IL1H2, IL-1F8, IL-1H2, IL1-ETA, FIL1-(ETA), FILI-(ETA), Interleukin-36 beta, FIL1 eta, IL-1 eta|IL36B
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-IL-36B antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the C-terminus of human IL-36B.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9NZH7
- Synonyms:
- family of interleukin 1-eta;FIL1;FIL1 eta;FIL1-(ETA);FIL1H;FILI-(ETA);IL-1 eta;IL-1F8;IL-1F8 (FIL1-eta);IL-1H2;IL1-ETA;IL1F8;IL1F8 (Canonical product IL-1F8a);IL1H2;interleukin 1 family, member 8 (eta);interleukin-1 eta;interleukin-1 family member 8;interleukin-1 homolog 2;Interleukin-1 Superfamily e;interleukin-36 beta
- Extra Details:
- IL-36B is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (4).
- Shipping Conditions:
- Blue Ice