600-401-BU1
IKK gamma Antibody
Cannot supply to this region.
- SKU:
- 600-401-BU1
- Additional Names:
- IKBKG|IKK gamma Antibody, IP, IP1, IP2, FIP3, IPD2, NEMO, FIP-3, Fip3p, AMCBX1, ZC2HC9, IKK-gamma, NF-kappa-B essential modulator
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-IKK gamma antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human IKK gamma.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9Y6K9
- Synonyms:
- 14.7K (adenovirus E3 protein) interacting protein 3;AMCBX1;EDAID1;FIP-3;FIP3;Fip3p;I-kappa-B kinase subunit gamma;ikB kinase subunit gamma;ikB kinase-associated protein 1;IKK-gamma;IKKAP1;IKKG;IMD33;incontinentia pigmenti;inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma;inhibitor of nuclear factor kappa B kinase subunit gamma;Inhibitor of nuclear factor kappa-B kinase subunit gamma;IP;IP1;IP2;IPD2;NEMO;NF-kappa-B essential modifier;NF-kappa-B essential modulator;ZC2HC9
- Extra Details:
- Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. The IkB kinase (IKKa and IKKb) phosphorylates IkB and mediates NF-kB activation. A novel molecule in the IKK complex was recently identified and termed IKKgamma/NEMO/FIP3/IKKAP1. IKKgamma interacts with IKKb and is required for the activation of IKK complex and NF-kB by LPS, PMA, TNF, and IL-1 stimulation. FIP3 was also shown to bind to RIP and NIK and to mediate TNF-induced NF-kB activation.
- Shipping Conditions:
- Dry Ice