600-401-BT3
IFIT3 Antibody
Cannot supply to this region.
- SKU:
- 600-401-BT3
- Additional Names:
- IFIT3|IFIT3 Antibody , P60, IRG2, IFI60, IFIT4, ISG60, RIG-G, CIG-49, GARG-49, Interferon-induced protein with tetratricopeptide repeats 3, CIG49, IFIT-3
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-IFIT3 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human IFIT3.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- O14879
- Synonyms:
- CIG-49;cig41;CIG49;GARG-49;IFI-60K;IFI60;IFIT-3;IFIT-4;IFIT4;interferon-induced 60 kDa protein;interferon-induced protein with tetratricopeptide repeats 3;interferon-induced protein with tetratricopeptide repeats 4;IRG2;ISG-60;ISG60;P60;retinoic acid-induced gene G protein;RIG-G
- Extra Details:
- The interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). IFIT3 has been shown to interact with TBK1 following RNA virus infection, thereby bridging TBK1 to VISA on the mitochondrion and activating IRF3 and thus the immune response (3).
- Shipping Conditions:
- Dry Ice