600-401-BT0
IDH2 Antibody
Cannot supply to this region.
- SKU:
- 600-401-BT0
- Additional Names:
- IDH2|IDH2 Antibody, IDH, IDP, IDHM, IDPM, ICD-M, D2HGA2, mNADP-IDHICD-M, IDH
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-IDH2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human IDH2.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P48735
- Synonyms:
- D2HGA2;ICD-M;IDH;IDHM;IDP;IDPM;isocitrate dehydrogenase (NADP(+)) 2, mitochondrial;isocitrate dehydrogenase [NADP], mitochondrial;isocitrate dehydrogenase 2 (NADP+), mitochondrial;mNADP-IDH;NADP(+)-specific ICDH;oxalosuccinate decarboxylase
- Extra Details:
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Two NADP(+)-dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. Both IDH1 and IDH2 play significant roles in the tricarboxylic acid cycle (TCA), and defects in IDH1 as well as IDH2 have been implicated in the development of glioma as well as other malignancies.
- Shipping Conditions:
- Blue Ice