600-401-BR1
HHATL Antibody
Cannot supply to this region.
- SKU:
- 600-401-BR1
- Additional Names:
- HHATL|HHATL Antibody, GUP1, OACT3, C3orf3, MBOAT3, MSTP002, GUP1, KIAA1173, Protein-cysteine N-palmitoyltransferase HHAT-like protein, Hedgehog acyltransferase-like protein
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-HHATL antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminus of human HHATL.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9HCP6
- Synonyms:
- C3orf3;glycerol uptake/transporter homolog;GUP1;GUP1 glycerol uptake/transporter homolog;hedgehog acyltransferase-like protein;MBOAT3;membrane bound O-acyltransferase domain containing 3;MSTP002;OACT3;protein-cysteine N-palmitoyltransferase HHAT-like protein
- Extra Details:
- The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development.
- Shipping Conditions:
- Dry Ice