600-401-BH2
FREM2 Antibody
Cannot supply to this region.
- SKU:
- 600-401-BH2
- Additional Names:
- FREM2|FREM2 Antibody, FRAS1-related extracellular matrix protein 2, ECM3 homolog
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-FREM2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the internal region of human FREM2.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q5SZK8
- Synonyms:
- CRYPTOP;ECM3 homolog;FRAS1 related extracellular matrix protein 2;FRAS1-related extracellular matrix protein 2;FRASRS2
- Extra Details:
- FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affected by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
- Shipping Conditions:
- Dry Ice