600-401-BC7
F1A alpha Antibody
Cannot supply to this region.
- SKU:
- 600-401-BC7
- Additional Names:
- F1A alpha Antibody, F1AA, F1A-ALPHA, FEM1-beta, F1AA, KIAA0396, Protein fem-1 homolog B, FEM1b|FEM1B
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-F1A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the C-terminus of human F1A.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9UK73
- Synonyms:
- F1A-ALPHA;F1AA;FEM-1-like death receptor binding protein;fem-1-like death receptor-binding protein alpha;fem-1-like in apoptotic pathway protein alpha;FEM1-beta;protein fem-1 homolog B
- Extra Details:
- Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1b. F1Aalpha/FEM1b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues.
- Shipping Conditions:
- Dry Ice