CX3CL1 Antibody

Cannot supply to this region.

SKU:: 600-401-AR2
Additional Names:: CX3CL1|CX3CL1 Antibody, NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin, FKN, A-152E5.2, Fractalkine, C-X3-C motif chemokine 1
Application:: ELISA, WB, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:: Anti-CX3CL1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 18 amino acids near the N-terminus of human CX3CL1.
Formulation:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:: P78423
Synonyms:: ABCD-3;C-X3-C motif chemokine 1;C3Xkine;chemokine (C-X3-C motif) ligand 1;CX3C membrane-anchored chemokine;CXC3;CXC3C;fractalkine;neurotactin;NTN;NTT;SCYD1;small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin);small inducible cytokine subfamily D (Cys-X3-Cys), member-1;small-inducible cytokine D1
Extra Details:: Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.

Shipping Conditions:: Dry Ice