600-401-AG6
CCR8 Antibody
Cannot supply to this region.
- SKU:
- 600-401-AG6
- Additional Names:
- CCR8|CCR8 Antibody, CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-CCR8 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the internal region of human CCR8.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P51685
- Synonyms:
- C-C chemokine receptor type 8;CC chemokine receptor 8;CC chemokine receptor CHEMR1;CC-chemokine receptor chemr1;CC-CKR-8;CCR-8;CDw198;chemokine (C-C motif) receptor 8;chemokine (C-C) receptor 8;chemokine (C-C) receptor-like 2;chemokine receptor-like 1;CKRL1;CMKBR8;CMKBRL2;CY6;GPR-CY6;GPRCY6;TER1
- Extra Details:
- CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
- Shipping Conditions:
- Dry Ice