600-401-AC5
Caspase-1 Antibody
Cannot supply to this region.
- SKU:
- 600-401-AC5
- Additional Names:
- CASP1|Caspase-1 Antibody, ICE, P45, IL1BC, IL1BCE, Caspase-1, Interleukin-1 beta convertase, CASP-1
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-Caspase-1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the internal region of human Caspase-1.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P29466
- Synonyms:
- CASP1 nirs variant 1;caspase 1, apoptosis-related cysteine peptidase;caspase-1;caspase-1 isoform alpha;ICE;IL-1 beta-converting enzyme;IL1B-convertase;IL1BC;interleukin 1-B converting enzyme;interleukin 1, beta, convertase;Interleukin-1 beta convertase;Interleukin-1 beta-converting enzyme;P45
- Extra Details:
- Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-1 was initially identified as an IL-1b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.
- Shipping Conditions:
- Dry Ice