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  2. Polyclonal

600-401-461

MAD2L1 Antibody

Cannot supply to this region.

SKU:
600-401-461
Additional Names:
MAD2L1|rabbit anti-MAD2L1 antibody, MAD2, MAD2-like protein 1, HsMAD2, Mitotic arrest deficient 2-like protein 1, Mitotic spindle assembly checkpoint protein MAD2A
Application:
ELISA, WB, IF
Concentration:
1.19 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Host:
Rabbit
Reactivities:
Human
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to N-terminal region near amino acid residues 1-25 of Human MAD2L1 protein.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Uniprot:
Q13257
Synonyms:
HSMAD2;MAD2;MAD2 (mitotic arrest deficient, yeast, homolog)-like 1;MAD2 mitotic arrest deficient-like 1;MAD2-like protein 1;mitotic arrest deficient 2-like protein 1;mitotic arrest deficient, yeast, homolog-like 1;mitotic spindle assembly checkpoint protein MAD2A
Extra Details:
MAD2L1 (also called mitotic spindle assembly checkpoint protein, MAD2A, MAD2-like 1 and HsMAD2) is a component of the mitotic spindle assembly checkpoint monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. MAD2L1 inhibits the activity of the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. This protein has a nuclear localization.
Shipping Conditions:
Dry Ice