600-401-351
APC10 Antibody
Cannot supply to this region.
- SKU:
- 600-401-351
- Additional Names:
- ANAPC10|rabbit anti-APC10 antibody, APC-10, APC 10, ANAPC10, ANAPC-10, APC, Anaphase Promoting Complex, Cyclosome subunit 10, anaphase-promoting complex subunit 10
- Application:
- ELISA, IHC, WB, IP
- Concentration:
- 1.5 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the amino terminus of human APC10.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9UM13
- Synonyms:
- anaphase-promoting complex subunit 10;APC10;cyclosome subunit 10;DOC1
- Extra Details:
- APC (Anaphase-Promoting Complex or Cyclosome) is a ubiquitin ligase which specifically targets mitotic regulatory factors such as Pds1/Cut2 and cyclin B. It was found that APC10/Doc1 is localized in centrosomes and mitotic spindles throughout mitosis, while it is also localized in kinetochores from prophase to anaphase and in mid-body in telophase and cytokinesis. These results strongly support the notion that human APC10/Doc1 may be one of the APC core subunits rather than the transiently associated regulatory factor.
- Shipping Conditions:
- Dry Ice