600-101-196
Apolipoprotein A-I Antibody
Cannot supply to this region.
- SKU:
- 600-101-196
- Additional Names:
- Apoa1|goat anti-Apolipoprotein A-I Antibody, goat anti-APOA1 antibody, goat anti-APO-A1 antibody, goat anti-APOA-1 antibody, APOA1/APOC3 fusion gene antibody, Apolipoprotein A I precursor antibody, Apolipoprotein AI antibody, Apolipoprotein of high density lipoprotein antibody, ProapoA-I, Proapolipoprotein A-I
- Application:
- ELISA, IHC, WB, IF, IP
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C 50% glycerol. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Goat
- Reactivities:
- Mouse
- Buffer:
- 0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA
- Immunogen:
- apoLipoprotein Type A-I was isolated from mouse plasma by density gradient centrifugation followed by HPLC purification.
- Formulation:
- 0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA, pH 8.0
- Uniprot:
- Q00623
- Synonyms:
- Al;Alp-1;Ap;apo-AI;Apoa-1;apoA-I;apolipoprotein A-I;apolipoprotein A1;Brp-;Brp-14;Ltw-;Ltw-1;Lvtw;Lvtw-1;Se;Sep;Sep-1;Sep-2;Sep2
- Extra Details:
- Anti Apolipoprotein A-I antibody recognizes the gene product of APOA1. Apolipoprotein promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18-amino acid signal peptide is removed co-translationally and a 6-amino acid propeptide is cleaved post-translationally. Variation in the latter step, in addition to modifications leading to so-called isoforms, is responsible for some of the polymorphism observed. APOA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the C-III gene is transcribed convergently in relation to A-I. Defects in the apolipoprotein A-1 gene are associated with HDL deficiency and Tangier disease. This antibody is suitable for cardiovascular research.
- Shipping Conditions:
- Blue Ice