212-401-B32
IL-17A Antibody
Cannot supply to this region.
- SKU:
- 212-401-B32
- Additional Names:
- Il17a|rabbit anti-IL-17A Antibody, rabbit anti-Interleukin-17A Antibody, Interleukin17, IL-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Lyophilized
- Species Reactivity:
- Rat
- Storage Conditions:
- 2-8[o]C liquid. Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant rat IL17-A protein.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q61453, Q61453.1
- Synonyms:
- CTLA-8;cytotoxic T-lymphocyte-associated antigen 8;IL-17;IL-17A;Il17;Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8);interleukin-17A
- Extra Details:
- Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and rat IL-17A.
- Shipping Conditions:
- Ambient