BAX Antibody

Cannot supply to this region.

SKU:: 200-C01-B34
Additional Names:: BAX|BAX Bcl-2-like protein 4 BCL2L4
Application:: ELISA, Flow Cytometry, IHC, WB
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:: This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human BAX protein. The hybridoma was produced by fusing New Zealand White rabbit splenocytes and myeloma cells using conventional technology.
Formulation:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Clone:: SP47
Uniprot:: Q07812
Synonyms:: apoptosis regulator BAX;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;bcl-2-like protein 4;BCL2 associated X protein;BCL2-associated X protein omega;bcl2-L-4;BCL2L4
Extra Details:: BAX, also known as Bcl-2-like protein 4 and BCL2L4 is known to accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX induces the release of cytochrome c, activation of CASP3, and thereby apoptosis. BAX protein is expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin. Isoform Alpha and isoform Sigma are expressed in pro-myelocytic leukemia, histiocytic lymphoma, Burkitt's lymphoma, T-cell lymphoma, lymphoblastic leukemia, breast adenocarcinoma, ovary adenocarcinoma, prostate carcinoma, prostate adenocarcinoma, lung carcinoma, epidermoid carcinoma, small cell lung carcinoma and colon adenocarcinoma cell lines. Isoform alpha is considered to be the 'canonical' sequence.

Shipping Conditions:: Blue Ice