Eaat1 Antibody

Cannot supply to this region.

SKU:: 200-901-ML1
Additional Names:: Chicken Anti-Slc1a3 Antibody, Chicken Anti-Eaat1 Antibody, Excitatory amino acid transporter 1, Glial glutamate transporter, Sodium-dependent glutamate/aspartate transporter 1, GLAST, GAST-1, Slc1a3, Eaat1|Slc1a3
Application:: ELISA, WB, IF
Concentration:: 0.99 mg/ml
Physical State:: Liquid
Species Reactivity:: Rat
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Chicken/Avian
Reactivities:: Rat
Buffer:: 0.002 M Sodium Phosphate, 0.15 M Sodium Chloride
Immunogen:: Anti-Slc1a3 antibody was prepared from eggs of chickens laid after repeated immunizations with a synthetic peptide corresponding to a N-Terminal portion of rat Slc1a3 conjugated to Keyhole Limpet Hemocyanin (KLH).
Formulation:: 0.002 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.0
Uniprot:: P24942
Synonyms:: EAAT1;excitatory amino acid transporter 1;GLAST;GLAST-1;glial glutamate transporter;GluT-1;glutamate transporter;glutamate/aspartate transporter;sodium-dependent glutamate/aspartate transporter 1;solute carrier family 1 (glial high affinity glutamate transporter), member 3;Solute carrier family 1 member 3
Extra Details:: Slc1a3 (or Eaat1) is widely distributed throughout the brain. It is a potassium and sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate, L-aspartate, and D-aspartate. It functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. It mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Slc1a3 plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Slc1a3 can play a role in Episodic Ataxia, Type 6 and Wernicke Encephalopathy. Anti-Slc1a3 Antibody is useful for researchers interested in SIDS, Glucose Metabolism, and Glutamate and Amino Acid Binding.

Shipping Conditions:: Dry Ice