200-901-EM2
SIRT7 Antibody
Cannot supply to this region.
- SKU:
- 200-901-EM2
- Additional Names:
- SIRT7|SIRT7 Antibody, SIR2L7, SIR2L7, NAD-dependent protein deacetylase sirtuin-7, Regulatory protein SIR2 homolog 7
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Chicken/Avian
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-SIRT7 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminus of human SIRT7.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9NRC8
- Synonyms:
- NAD-dependent deacetylase sirtuin-7;NAD-dependent protein deacetylase sirtuin-7;NAD-dependent protein deacylase sirtuin-7;regulatory protein SIR2 homolog 7;silent mating type information regulation 2, S.cerevisiae, homolog 7;SIR2-like protein 7;sir2-related protein type 7;SIR2L7;sirtuin type 7
- Extra Details:
- The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.
- Shipping Conditions:
- Dry Ice