200-526-M73
CD25 APC Antibody
Cannot supply to this region.
- SKU:
- 200-526-M73
- Additional Names:
- Il2r|Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25 Antibody
- Application:
- Flow Cytometry
- Concentration:
- 0.2 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Mouse
- Storage Conditions:
- 2-8[o]C unopened. Protect from light.
- Supplier:
- Rockland Inc
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-CD25 Antibody (Monoclonal) was produced by repeated immunizations with IL-2-dependent cytolytic mouse T-cell clone B6.1.
- Formulation:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- PC61
- Uniprot:
- P01590
- Synonyms:
- CD25;I;IL-2 receptor subunit alpha;IL-2-RA;IL-2R alpha chain;IL-2R subunit alpha;IL2-RA;Il2r;interleukin-2 receptor subunit alpha;Ly-4;Ly-43;p55;p55 chain
- Extra Details:
- CD25 is a 55KDa transmembrane glycoprotein consisting of a heavily glycosylated extracellular domain, a transmembrane region and a short cytoplasmic tail. It is expressed during early stages of thymocytes development and in activated CD4+ memory T-lymphocytes. CD25 heterodimerizes with IL2R-beta and IL-2R gamma and forms the tripartite high affinity IL-2 receptor complex. It increases the specificity and affinity of IL-2 receptor complex for IL-2 ligand and is necessary for receptor clustering required for augmentation of IL-2 signaling. Mutations in CD25 result in severe immunodeficiency.
- Shipping Conditions:
- Blue Ice