200-526-E71
AKT2 APC Antibody
Cannot supply to this region.
- SKU:
- 200-526-E71
- Additional Names:
- AKT2|rat anti-Anti-AKT2 Allophycocyanin Conjugation, APC Conjugated rat anti-Anti-AKT2, AKT 2 antibody, AKT-2, PKB antibody, PKB beta antibody, PKBBETA antibody, PRKBB antibody, Protein kinase Akt 2 antibody, Protein kinase B beta antibody, RAC-beta serine/threonine-protein kinase, RAC-PK-beta
- Application:
- ELISA, Flow Cytometry, IHC, WB, IF, Dot blot
- Concentration:
- 1 mg/ml
- Physical State:
- Lyophilized
- Species Reactivity:
- Human
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Rat
- Reactivities:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.5 M Sodium Chloride
- Immunogen:
- Anti-AKT2 Antibody was produced in rat by repeated immunizations with a synthetic peptide corresponding to internal residues of human AKT2 protein.
- Formulation:
- 0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2
- Clone:
- 16G11.E8
- Uniprot:
- P31751
- Synonyms:
- HIHGHH;murine thymoma viral (v-akt) homolog-2;PKB beta;PKBB;PKBBETA;PRKBB;protein kinase Akt-2;protein kinase B beta;putative v-akt murine thymoma viral oncoprotein 2;rac protein kinase beta;RAC-BETA;RAC-beta serine/threonine-protein kinase;RAC-PK-beta;v-akt murine thymoma viral oncogene homolog 2
- Extra Details:
- AKT is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as AKT1, Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. Anti-AKT2 (RAT) APC conjugated Monoclonal Antibody is ideal for investigators involved in Cell Signaling, Cancer, Neuroscience, Signal Transduction research.
- Shipping Conditions:
- Blue Ice