200-401-Z23
BAK Antibody
Cannot supply to this region.
- SKU:
- 200-401-Z23
- Additional Names:
- Bak Antibody, BAK, CDN1, BCL2L7, BAK-LIKE, BAK, Apoptosis regulator BAK, Bcl2-L-7|BAK1
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-Bak antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 13 amino acids near the amino-terminus of human Bak.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q16611
- Synonyms:
- apoptosis regulator BAK;BAK;BAK-LIKE;bcl-2 homologous antagonist/killer;bcl-2-like protein 7;bcl2-L-7;BCL2-like 7 protein;BCL2L7;CDN1;pro-apoptotic protein BAK
- Extra Details:
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria. It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability.
- Shipping Conditions:
- Dry Ice