LSD1 Antibody

Cannot supply to this region.

SKU:: 200-401-W52
Additional Names:: KDM1A|Lysine-specific histone demethylase 1A, BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2, AOF2, KDM1
Application:: ChIP, WB
Concentration:: 2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:: Anti-LSD1 Antibody was produced in rabbits by repeated immunizations with a full length recombinant protein of human LSD1.
Formulation:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:: O60341
Synonyms:: [histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A;amine oxidase (flavin containing) domain 2;AOF2;BHC110;BRAF35-HDAC complex protein BHC110;CPRF;FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit;flavin-containing amine oxidase domain-containing protein 2;KDM1;LSD1;lysine (K)-specific demethylase 1A;lysine-specific histone demethylase 1;lysine-specific histone demethylase 1A
Extra Details:: LSD1 (lysine specific demethylase 1) is a component of the histone demethylase complex that uses FAD as a prosthetic group. LSD1 may have a dual effect on gene transcription. As it demethylates the mono- and dimethylated 'Lys-4' of histone H3, which are associated with transcriptional activation, LSD1 can act as a repressor of gene expression. However, LSD1 is also capable of demethylating 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to activation of androgen receptor target genes. LSD1 therefore is ideal for research in different processes such as Stem and Cancer Cell Biology, Embryonic Development, Epigenetics and Cell Differentiation and Proliferation.

Shipping Conditions:: Dry Ice