200-401-H99
Nur77 Antibody
Cannot supply to this region.
- SKU:
- 200-401-H99
- Additional Names:
- GFRP1, HMR, NAK1, Nuclear receptor subfamily 4 group A member 1, Early response protein NAK1, Nuclear hormone receptor NUR/77, Nur77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3|NR4A1
- Application:
- ChIP, IHC, WB, IF, IP
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Nur77 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to internal amino acids with human Nur77 protein.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- P22736
- Synonyms:
- early response protein NAK1;GFRP1;growth factor-inducible nuclear protein N10;HMR;hormone receptor;N10;NAK-1;nerve growth factor IB nuclear receptor variant 1;NGFIB;NP10;nuclear hormone receptor NUR/77;nuclear receptor subfamily 4 group A member 1;NUR77;orphan nuclear receptor HMR;orphan nuclear receptor TR3;ST-59;steroid receptor TR3;testicular receptor 3;TR3;TR3 orphan receptor
- Extra Details:
- Anti Nur7 antibody detects human Nur77. Nur77 (Nak-1,TR3) is a member of the NR4A orphan nuclear receptor (NR) superfamily of transcription factors. The Nur77 ligand has not yet been identified. It is thought that the lack of ability to identify a ligand may be due to the lack of a typical NR binding pocket in the ligand binding domain. Nur77, like other NR4A receptors, are immediate-early genes induced by diverse stimuli in multiple tissues. There is increasing evidence that Nur77 and other NR4A receptors play important roles in maintaining tissue homeostasis. For example, specific Nur77 functions have been defined in the brain, T-cells/thymocytes, adipose tissue, steroidgenesis, muscle, blood vessels, macrophages and cardiovascular system. There is also evidence that Nur77 plays roles in pathological processes such as cancer. Nur77 is a phosphoprotein and its size ranges from ~65 kDa to 90 kDa depending on the isoform expressed and level of phosphorylation or other post-translational modifications. Anti-Nur77 antibody is ideal for investigators involved in apoptosis.
- Shipping Conditions:
- Dry Ice