200-401-FF8
TLR11 Antibody
Cannot supply to this region.
- SKU:
- 200-401-FF8
- Additional Names:
- Tlr11|TLR11 Antibody, Gm287, Gm287, Toll-like receptor 11
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-TLR11 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 16 amino acids between the internal region and C-terminus of mouse TLR11.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q6R5P0
- Synonyms:
- Gm287;toll-like receptor 11;toll-like receptor 12
- Extra Details:
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptibility to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
- Shipping Conditions:
- Dry Ice