200-401-FF4
TIRP Antibody
Cannot supply to this region.
- SKU:
- 200-401-FF4
- Additional Names:
- TICAM2|TIRP Antibody, TIRP, TRAM, TIRAP3, MyD88-4, TICAM-2, TIRP, TIR domain-containing adapter molecule 2, Putative NF-kappa-B-activating protein 502
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-TIRP antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 16 amino acids at the C-terminus of human TIRP.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q86XR7
- Synonyms:
- cytoplasmic adaptor;MyD88-4;NF-kappa-B-activating protein 502;putative NF-kappa-B-activating protein 502;TICAM-2;TICAM2;TIR domain-containing adapter molecule 2;TIRAP3;TIRP;TMED7-TICAM2 read-through transcript;toll-like receptor adaptor protein 3;toll/interleukin-1 receptor (TIR) domain-containing adapter protein;Toll/interleukin-1 receptor domain-containing protein;TRAM;TRAM adaptor with GOLD domain;TRIF-related adapter molecule;TRIF-related adaptor molecule
- Extra Details:
- TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kB. Expression of TIRP appears to be essential for TLR4 signaling.
- Shipping Conditions:
- Dry Ice