200-401-AX2
DR3 Antibody
Cannot supply to this region.
- SKU:
- 200-401-AX2
- Additional Names:
- DR3 Antibody, DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, WSL-LR, TNFRSF12, APO3, DR3, WSL, WSL1, UNQ455/PRO779, Tumor necrosis factor receptor superfamily member 25, Apo-3|TNFRSF25
- Application:
- ELISA, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-DR3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid peptide near the C-terminus of human DR3.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q93038
- Synonyms:
- APO-3;apoptosis inducing receptor;apoptosis-inducing receptor AIR;apoptosis-mediating receptor DR3;apoptosis-mediating receptor TRAMP;DDR3;death domain receptor 3 soluble form;Death receptor 3;death receptor beta;DR3;GEF720;Guanine nucleotide exchange factor 720;LARD;lymphocyte-associated receptor of death;PH domain-containing family G member 5;Pleckstrin homology domain-containing family G member 5;PLEKHG5;Protein WSL;protein WSL-1;TNFRSF12;TR3;TRAMP;tumor necrosis factor receptor superfamily member 25;tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein);WSL-1;WSL-LR
- Extra Details:
- Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel cell death receptor has not yet been defined. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kB activation.
- Shipping Conditions:
- Dry Ice