200-401-A64
TLR7 Antibody
Cannot supply to this region.
- SKU:
- 200-401-A64
- Additional Names:
- PRO285 antibody, Toll like receptor 7 antibody, UNQ248 antibody|Tlr7
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- TLR7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to an internal region of mouse TLR7.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- P58681
- Synonyms:
- Toll like receptor 7;toll-like receptor 7
- Extra Details:
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFN secretion, suggesting the importance of TLR7 in virus recognition. Anti-TLR7 antibody is ideal for investigators involved in kinases, phosphatase, cytokines, growth factors and transcription factor research.
- Shipping Conditions:
- Dry Ice