200-326-N25
CD25 APC Antibody
Cannot supply to this region.
- SKU:
- 200-326-N25
- Additional Names:
- IL2RA|Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55
- Application:
- Flow Cytometry
- Concentration:
- 0.025 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C unopened. Protect from light.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-CD25 Antibody (Monoclonal) was produced by repeated immunizations with CD25 antigen.
- Formulation:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- BC96
- Uniprot:
- P01589
- Synonyms:
- CD25;IDDM10;IL-2 receptor subunit alpha;IL-2R subunit alpha;IL2R;IMD41;interleukin 2 receptor, alpha;interleukin-2 receptor subunit alpha;p55;TAC antigen;TCGFR
- Extra Details:
- The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells. The BC96 antibody may be used as a marker for expression of CD25 during T and B cell development, on activated mature T and B cells, and for its expression at high levels on natural T regulatory cells (nTreg cells) in the thymus or periphery, and on induced peripheral Tregs.
- Shipping Conditions:
- Blue Ice