200-326-M64
CD8 APC Antibody
Cannot supply to this region.
- SKU:
- 200-326-M64
- Additional Names:
- CD8A|T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL
- Application:
- Flow Cytometry
- Concentration:
- 0.05 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C unopened. Protect from light.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
- Formulation:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- RPA-T8
- Uniprot:
- P01732
- Synonyms:
- CD8;CD8 antigen, alpha polypeptide (p32);Leu2;Leu2 T-lymphocyte antigen;OKT8 T-cell antigen;p32;T cell co-receptor;T-cell antigen Leu2;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;T8 T-cell antigen
- Extra Details:
- CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.
- Shipping Conditions:
- Blue Ice