200-326-E75
AKT3 APC Antibody
Cannot supply to this region.
- SKU:
- 200-326-E75
- Additional Names:
- AKT3|Mouse anti-AKT3 antibody APC conjugation, Allophycocyanin conjugated Mouse anti-AKT 3 antibody, AKT-3, PKB antibody, PKB gamma antibody, PKBGAMMA antibody, PRKBG antibody, Protein kinase Akt 3 antibody, Protein kinase B gamma antibody, RAC-gamma serine/threonine-protein kinase, RAC-PK-gamma
- Application:
- ELISA, Flow Cytometry, IHC, WB, IF, Dot blot
- Concentration:
- 1 mg/ml
- Physical State:
- Lyophilized
- Species Reactivity:
- Human
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.5 M Sodium Chloride
- Immunogen:
- Anti-AKT3 Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to internal residues of human AKT3 protein.
- Formulation:
- 0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2
- Clone:
- 25F6.F6.D8
- Uniprot:
- Q9Y243
- Synonyms:
- MPPH;MPPH2;PKB gamma;PKB-GAMMA;PKBG;PRKBG;Protein kinase Akt-3;Protein kinase B gamma;RAC-gamma;RAC-gamma serine/threonine protein kinase;RAC-gamma serine/threonine-protein kinase;RAC-PK-gamma;STK-2;v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
- Extra Details:
- AKT is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as AKT1, Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. Anti-AKT3 (MOUSE) APC conjugated Monoclonal Antibody is ideal for investigators involved in Cell Signaling, Cancer, Neuroscience, Signal Transduction research.
- Shipping Conditions:
- Blue Ice