200-308-N67
CD40 Phycoerythrin Antibody
Cannot supply to this region.
- SKU:
- 200-308-N67
- Additional Names:
- BP50, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40|CD40
- Application:
- Flow Cytometry
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C unopened. Protect from light.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-CD40 Antibody (Monoclonal) was produced by repeated immunizations with CD40 antigen.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- 5C3
- Uniprot:
- P25942
- Synonyms:
- B cell surface antigen CD40;B cell-associated molecule;B-cell surface antigen CD40;Bp50;CD40 molecule, TNF receptor superfamily member 5;CD40L receptor;CDW40;p50;TNFRSF5;tumor necrosis factor receptor superfamily member 5
- Extra Details:
- CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
- Shipping Conditions:
- Blue Ice