CD3 Phycoerythrin Antibody

Cannot supply to this region.

SKU:: 200-308-N12
Additional Names:: CD3E|T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e
Application:: Flow Cytometry
Concentration:: 0.05 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: 2-8[o]C unopened. Protect from light.
Supplier:: Rockland Inc
Host:: Mouse
Reactivities:: Human
Buffer:: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
Immunogen:: Anti-CD3 Antibody (Monoclonal) was produced by repeated immunizations with CD3 antigen.
Formulation:: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Clone:: HIT3a
Uniprot:: P07766
Synonyms:: CD3-epsilon;CD3e antigen, epsilon polypeptide (TiT3 complex);CD3e molecule, epsilon (CD3-TCR complex);IMD18;T-cell antigen receptor complex, epsilon subunit of T3;T-cell surface antigen T3/Leu-4 epsilon chain;T-cell surface glycoprotein CD3 epsilon chain;T3E;TCRE
Extra Details:: The Hit3a antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells. The Hit3a antibody is a widely used phenotypic marker for human T cells. In addition, binding/cross-linking of Hit3a antibody to CD3e can induce cell activation. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3.

Shipping Conditions:: Blue Ice