200-306-W72
SHANK1/SHANK3 Antibody Biotin
Cannot supply to this region.
- SKU:
- 200-306-W72
- Additional Names:
- Shank postsynaptic density protein, SH3 and multiple ankyrin repeat domains 3, Proline rich synapse associated protein 2, Proline-rich synapse-associated protein 2, ProSAP2, PSAP2, SH3 and multiple ankyrin repeat domains protein 3|Shank3
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Rat
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-SHANK1/SHANK3 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 586-626 (SH3 domain) of rat SHANK3.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- S367-51
- Uniprot:
- Q9JLU4
- Synonyms:
- proline-rich synapse-associated protein 2;Prosap2;SH3 and multiple ankyrin repeat domains protein 3;SH3/ankyrin domain gene 3;Shank postsynaptic density protein 3a;Spank-2
- Extra Details:
- SHANK proteins are scaffolding adaptors that have been shown to integrate neurotransmitter receptors into the cortical cytoskeleton at postsynaptic densities. SHANK1-3 of the SHANK/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). SHANK recruits betaPIX and PAK to dendritic spines to regulate postsynaptic structure and interacts with ionotropic receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development. Anti-SHANK1/SHANK3 is ideal for research in Neuroscience, including autism spectrum disorder, and Cell Adhesion.
- Shipping Conditions:
- Blue Ice