![BIM Antibody [1C2C8]](https://rocklandwebimagescdn.azureedge.net/webimages/200-301-Z71-Bim-1-IHC-4x3.jpg)
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200-301-Z71
BIM Antibody [1C2C8]
Cannot supply to this region.
- SKU:
- 200-301-Z71
- Additional Names:
- BCL2L11|Bim Antibody, BAM, BIM, BOD, BCL2L11
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-Mouse monoclonal Bim antibody produced by repeated immunizations in mice with a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Clone:
- 1C2C8
- Uniprot:
- O43521
- Synonyms:
- BAM;bcl-2 interacting mediator of cell death;bcl-2 interacting protein Bim;bcl-2-like protein 11;bcl-2-related ovarian death agonist;Bcl2-interacting mediator of cell death;BCL2-like 11 (apoptosis facilitator);BIM;BOD
- Extra Details:
- Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
- Shipping Conditions:
- Dry Ice