200-301-W59
LRRK2/Dardarin Antibody
Cannot supply to this region.
- SKU:
- 200-301-W59
- Additional Names:
- Leucine-rich repeat kinase 2, RIP7, PARK8, Dardarin, ROCO 2, RIPK7, Leucine-rich repeat serine/threonine-protein kinase 2, augmented in rheumatoid arthritis 17|LRRK2
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-LRRK2/Dardarin Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 841-960 of human LRRK2.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- S231B-34
- Uniprot:
- Q5S007
- Synonyms:
- augmented in rheumatoid arthritis 17;AURA17;DARDARIN;leucine-rich repeat serine/threonine-protein kinase 2;PARK8;RIPK7;ROCO2
- Extra Details:
- LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Anti-LRRK2 is ideal for researchers interested in Neuroscience, specifically parkinsonism, as well as pathways related to the Electron Transport Chain and Wnt Signaling.
- Shipping Conditions:
- Blue Ice